Vaccines - Post-splenectomy prophylaxis
After splenectomy, the absence of antibodies allows for rapid proliferation of encapsulated organisms (S. pneumonia, N. meningitides, H. influenza.)
S. pneumonia is the MCC of sepsis in post-splenectomy patients.
- S. pneumonia (PCV13 followed by PPSV23 8 weeks later). Revaccinate with PPSV23 five years later and at age 65.
- H. influenzae type B
- TDaP, HAV, HVB according to standard guidelines