Pancreatic adenocarcinoma

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Risk factors

  • Smoking
  • Hereditary pancreatitis
  • Chronic pancreatitis
  • Obesity, sedentarism

Presentation

  • Weight loss, anorexia, fatigue
  • Abdominal pain, back pain
  • Jaundice
  • Recent onset DM
  • Migratory superficial thrombophlebitis
  • Hepatomegaly

Findings

  • alkaline phosphatase and direct bilirubin
  • CA 19-9 (not for screening)
  • US (if jaundiced) or CT (if no jaundice)