Milk/soy-protein-induced colitis (milk protein allergy)

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Non-IgE immune response to dairy/soy proteins

Risk factors

  • FHx of allergies
  • Eczema
  • Asthma


  • Age 2-8 weeks
  • Regurgitation/vomiting
  • ± Painless bloody stools
  • ± eczema


Bleeding ceases with dietary modifications


  • Elimination of milk/soy from maternal diet of exclusively breastfed infants
  • Initiate hydrolyzed formula in formula-fed infants
  • Spontaneous resolution by age 1 year