GI-Tropical Sprue

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Risk factor

Living in endemic areas (Puerto Rico) for > 1 month


  • Chronic diarrhea
  • Malabsorption (esp. B12 and folate megaloblastic anemia)
  • Glossitis, cheilosis, pallor, pedal edema


Small intestinal mucosal biopsy (shows blunting of villi and infiltration of lymphocytes, plasma cells, and eosinophils)

Differential diagnosis

Celiac disease (history of travek favors Sprue), infectious diarrhea (get a stool tests)