Blastomycosis

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Great lakes, Mississippi river and Ohio River basins (Wisconsin)

Presentation

  • Low-grade fever, night sweats, productive cough, weight loss
  • Ulcerated skin lesions
  • Lytic bone lesions

Diagnosis

Sputum culture: Broad-based budding yeast

Treatment

  • Itraconazole
  • Amphotericin B